Articles

Off-label marketing: How testosterone replacement got big

By Chris Adams, McClatchy Newspapers

WASHINGTON — The question for doctors was simple: "When a patient comes in and asks for Viagra, will you first screen for low T?" meaning testosterone.

The pitch by Solvay Pharmaceuticals Inc. was part of its effort to make its testosterone replacement drug AndroGel "ride (the) coat tails of Viagra."

But unlike Viagra, AndroGel wasn't approved by the Food and Drug Administration to treat erectile dysfunction.

Menopause Experts Back Hormone Therapy

BHI

June 10, 2011 -- The message was clear from the International Menopause Society – Hormone Replacement Therapy (HRT) is safe for most women in menopause but that tr

Comment: Are the problems with Actos and Avandia due to drug company greed or a broken system?

Kent Holtorf, M.D.

John Gever, Senior Editor of MedPage Today recently publish an artitle entitled Cancer Risk Forces Actos Off French, German Markets. In it he reports drug regulators in Germany and France have ordered doctors to stop prescribing the type 2 diabetes drug pioglitazone (Actos) following a French study suggesting a heightened risk of bladder cancer.

 

Some Postmenopausal Women Not on HRT Have Endometrial Lining Suspicious for Polyps

Alice Goodman, Elsevier Global Medical News

WASHINGTON (EGMN) – A small but important percentage of postmenopausal women not taking hormone replacement therapy have an endometrial lining that is suspicious for polyps, according to a prospective study of 1,500 consecutive asymptomatic women.

FDA restricts use of simvastatin 80 mg

BHI

The Food and Drug Administration is recommending that physicians restrict prescribing high-dose simvastatin (Zocor, Merck) to patients, given an increased risk of muscle damage [1]. The new FDA drug safety communication, issued today, states that physicians should limit using the 80-mg dose unless the patient has already been taking the drug for 12 months and there is no evidence of myopathy.

Click HERE to read the full FDA safety communication.

Related Articles:

ENDO: Estrogen Levels Pre-HRT Speak to Heart Risk

Kristina Fiore, Staff Writer, MedPage Today

June 7, 2011 Boston -- Women who have higher levels of endogenous estrogen before starting hormone therapy appear to have a lower risk of heart disease, according to a subgroup analysis of the Women's Health Initiative (WHI) data reported here.

Researchers Find Age Does Not Affect Testosterone in Healthy Men

WebMD

June 7, 2011 -- Testosterone decline is not inevitable with age, according to Australian scientists. Older men in excellent health can maintain their hormone levels, they say.

''What we found was, when you consider all the possible influences, age had no effect on testosterone levels in these very healthy men," says researcher David Handelsman, MD, PhD, director of the ANZAC Research Institute at the University of Sydney.

Flaxseed No Help for Menopausal Hot Flashes

BHI

A new study presented this week at the annual meeting of the American Society of Clinical Oncology in Chicago, reported that a daily flaxseed bar was no more effective than a placebo in helping with hot flashes in women with or without breast cancer. 188 women were involved in the study and researchers from the Mayo Clinic and North Central Cancer Treatment Group (NCCTG) found that taking 40g of crushed flaxseed did not affect women's hot flashes. This finding contradicts earlier research by the same group.

Comment: Increased Risk of Blood Clots Seen with Yaz/Yazmin

Dr Kent Holtorf, M.D.

In a safety announcement yesterday (05-31-2011), the U.S. Food and Drug Administration (FDA) informed the public about new information that is being assessed as part of FDA's ongoing safety review of birth control pills that contain drospirenone. This review will further evaluate the risk of blood clots in women who use these products.

In response to this announcement, Dr Kent Holtorf, M.D., Director of the Bioidentical Hormone Initiative makes the following observation:

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